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CGP 53716

CAT: 0804-HY-101837-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101837-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CGP 53716 is a potent protein tyrosine kinase inhibitor. CGP 53716 has selective activity of platelet-derived growth factor (PDGF) receptor. CGP 53716 can be used in the study of disease induced by abnormal cell proliferation induced by PDGF receptor activation [1].
CAS Number
152459-94-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PDGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cgp-53716.html
Purity
98.20
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=C(C)C(NC2=NC=CC(C3=CC=CN=C3)=N2)=C1)C4=CC=CC=C4
Molecular Formula
C23H19N5O
Molecular Weight
381.43
Precautions
H302, H315, H319, H335
References & Citations
[1]Buchdunger E, et al. Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class. Proc Natl Acad Sci U S A. 1995 Mar 28;92 (7) :2558-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1

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