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CP 316311

CAT: 0804-HY-14129-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-14129-01Size:1 mg
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Description
CP 316311 is a potent and selective CRF1 receptor antagonist with an IC50 value of 6.8 nM.
CAS Number
[175139-41-0]
UNSPSC
12352005
Target
CRFR
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/CP_316311.html
Solubility
10 mM in DMSO
Smiles
CCC(CC)OC1=C(C)C(OC2=C(C)C=C(C)C=C2C)=NC(C)=C1
Molecular Formula
C21H29NO2
Molecular Weight
327.46
References & Citations
[1]Chen YL, et al. Synthesis and SAR of 2-aryloxy-4-alkoxy-pyridines as potent orally active corticotropin-releasing factor 1 receptor antagonists. J Med Chem. 2008 Mar 13;51 (5) :1377-84.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
CRFR1

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