CP 316311

• Description:

  CP 316311 is a potent and selective CRF1 receptor antagonist with an IC50 value of 6.8 nM.

• UNSPSC:

  12352005

• Target:

  CRFR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Neurological Disease; Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/CP_316311.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCC(CC)OC1=C(C)C(OC2=C(C)C=C(C)C=C2C)=NC(C)=C1

• Molecular Formula:

  C21H29NO2

• Molecular Weight:

  327.46

• References & Citations:

  [1]Chen YL, et al. Synthesis and SAR of 2-aryloxy-4-alkoxy-pyridines as potent orally active corticotropin-releasing factor 1 receptor antagonists. J Med Chem. 2008 Mar 13;51 (5) :1377-84.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• Isoform:

  CRFR1

• CAS Number:

  [175139-41-0]