CP 316311

• Description :

  CP 316311 is a potent and selective CRF1 receptor antagonist with an IC50 value of 6.8 nM.

• CAS Number :

  [175139-41-0]

• UNSPSC :

  12352005

• Target :

  CRFR

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Neurological Disease; Endocrinology

• Assay Protocol :

  https://www.medchemexpress.com/CP_316311.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CCC(CC)OC1=C(C)C(OC2=C(C)C=C(C)C=C2C)=NC(C)=C1

• Molecular Formula :

  C21H29NO2

• Molecular Weight :

  327.46

• References & Citations :

  [1]Chen YL, et al. Synthesis and SAR of 2-aryloxy-4-alkoxy-pyridines as potent orally active corticotropin-releasing factor 1 receptor antagonists. J Med Chem. 2008 Mar 13;51 (5) :1377-84.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• Isoform :

  CRFR1