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CP 376395

CAT: 0804-HY-14130-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14130-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CP 376395 is a potent, selective, and brain-penetrable Corticotropin releasing factor 1 (CRF1) receptor antagonist[1][2].
CAS Number
175140-00-8
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
CRFR
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/CP_376395.html
Concentration
10mM
Purity
99.68
Solubility
DMSO : ≥ 100 mg/mL
Smiles
CCC(CC)NC1=C(C)C(OC2=C(C)C=C(C)C=C2C)=NC(C)=C1
Molecular Formula
C21H30N2O
Molecular Weight
326.48
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Chen YL, et al. 2-aryloxy-4-alkylaminopyridines: discovery of novel corticotropin-releasing factor 1 antagonists. J Med Chem. 2008 Mar 13;51 (5) :1385-92.|[2]Giardino WJ, et al. CRF1 receptor signaling regulates food and fluid intake in the drinking-in-the-dark model of binge alcohol consumption. Alcohol Clin Exp Res. 2013 Jul;37 (7) :1161-70.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CRFR1; CRFR2

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Alternative Products

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MBS3607367-01CP 376395
524836CP-376395 HCl
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A21973-50CP 376395 50mg
A21973-25CP 376395 25mg
A21973-10CP 376395 10mg
A21973-1CP 376395 1mg
A21973-100CP 376395 100mg
A21973-5CP 376395 5mg
555143CP-376395 free base

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