Products for Research Use Only
RegisterLogin

AMPK-IN-3

CAT: 0804-HY-151361-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-151361-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
AMPK-IN-3 (compound 67) is a potent and selective AMPK inhibitor with IC50s of 60.7, 107 and 3820 nM for AMPK (α2), AMPK (α1) and KDR, respectively. AMPK-IN-3 inhibits AMPK does not affect cell viability or cause significant cytotoxicity in K562 cells. AMPK-IN-3 can be used in study of cancer[1].
CAS Number
2417674-27-0
UNSPSC
12352005
Target
AMPK
Type
Reference compound
Related Pathways
Epigenetics; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ampk-in-3.html
Purity
98.51
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(/C(C1=C2)=C\C3=C(C(C(NCCN(CC)CC)=O)=C(N3)C)C)NC1=CC=C2CCC(N)=O
Molecular Formula
C25H33N5O3
Molecular Weight
451.56
References & Citations
[1]Matheson CJ, et al. Substituted oxindol-3-ylidenes as AMP-activated protein kinase (AMPK) inhibitors. Eur J Med Chem. 2020 Jul 1;197:112316.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-162317AMPK-IN-5
HY-155943-01AMPK-IN-4
HY-120904-01AMPK-IN-1
HY-172094AMPK-IN-6
HY-149406-01AMPK activator 12
HY-147037AMPK activator 7
HY-170931AMPK activator 16
HY-155363-01AMPK activator 13
HY-172901AMPK activator 17
HY-168639AMPK activator 15

Alternative Products

CatalogName
M35664-01AMPK-IN-3
CST 2550TAMPKγ3 Antibody
sc-72114-PRAMPKγ3 (m) -PR
sc-38933-PRAMPKγ3 (h) -PR
sc-38933AMPKγ3 siRNA (h)
sc-72114AMPKγ3 siRNA (m)
341822-01AMPKγ1/2/3 discontinued
C10728-01AMPKγ1/2/3 Antibody
sc-38933-SHAMPKγ3 shRNA Plasmid (h)
sc-72114-SHAMPKγ3 shRNA Plasmid (m)

Popular Products