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TAAR1 agonist 2

CAT: 0804-HY-W909173Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W909173Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TAAR1 agonist 2 (compound 30) is a full agonist of trace amine-associated receptor 1 (TAAR1) (pEC50=7.5) . TAAR1 agonist 2 also exhibits agonist activity at H1 receptors and activates several members of the muscarinic acetylcholine receptor family, such as the M2 receptor (pEC50=5) . TAAR1 agonist 2 can be used in the study of neuropsychiatric diseases[1].
CAS Number
1804128-38-8
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Histamine Receptor; mAChR; Trace Amine-associated Receptor (TAAR)
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/taar1-agonist-2.html
Smiles
C1(C2=CCCNC2)=CC=CO1
Molecular Formula
C9H11NO
Molecular Weight
149.19
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Díaz-Holguín, et al. "AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine–associated receptor 1." Science Advances 10.32 (2024) : eadn1524.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAChR2

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