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TAAR1 agonist 1

CAT: 0804-HY-157955Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157955Size:1 Each
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Description
TAAR1 agonist 1 (compound 6E) is a potent TAAR1 agonist with a potent TAAR1-Gs/Gq dual-pathway activation property. TAAR1 agonist 1 significantly alleviates MK-801-induced schizophrenia-like cognitive phenotypes[1].
UNSPSC
12352005
Target
Trace Amine-associated Receptor (TAAR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/taar1-agonist-1.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(C2=CC=CO2)C=C1)[C@H](N)C
Molecular Formula
C13H14N2O2
Molecular Weight
230.26
References & Citations
[1]Zhenzhen Zhou, et al. Structure-Based Design of Novel G-Protein-Coupled Receptor TAAR1 Agonists as Potential Antipsychotic Drug Candidates. J Med Chem. 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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