CB2R agonist 4

• Description:

  CB2R agonist 4 is a cannabinoid receptor 2 (CB2R) agonist with an EC50 value of 6.9 μM. CB2R agonist 4 can induce cell apoptosis, ROS production and protein misfolding. CB2R agonist 4 shows cytotoxicity to a panel of tumor cell lines. CB2R agonist 4 can be used for the research of cancer[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis; Cannabinoid Receptor; Reactive Oxygen Species (ROS)

• Related Pathways:

  Apoptosis; GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Smiles:

  O=C (OCC1=CC=CC=C1) [C@@H] (N2C (C3=CC=CC=C3NC2=O) =O) CC (C) C

• Molecular Formula:

  C21H22N2O4

• Molecular Weight:

  366.41

• References & Citations:

  [1]Ciaglia T, et al. Untargeted Diversity-Oriented Synthesis for the Discovery of New Antitumor Agents: An Integrated Approach of Inverse Virtual Screening, Bioinformatics, and Omics for Target Deconvolution. J Med Chem. 2025 Aug 14;68 (15) :16483-16517.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  CB2

• CAS Number:

  182496-82-8