MKP-1/2 Colorimetric Cell-Based ELISA Kit

• Description:

  The MKP-1/2 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MKP-1/2 protein expression profile in cells. The kit can be used for measuring the relative amounts of MKP-1/2 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MKP-1/2.

• Synonyms:

  3CH134; CL100; Dual specificity protein phosphatase 1; Dual specificity protein phosphatase hVH1; DUS1; DUSP1; MAP kinase phosphatase-1; MKP1; Protein-tyrosine phosphatase 3CH134; Protein-tyrosine phosphatase CL100; Protein-tyrosine phosphatase ERP; PTPN10; PTPN16; VH1

• Gene Name:

  DUSP1 CL100 , MKP1, PTPN10 , VH1

• UniProt:

  P28562

• Reactivity:

  Human, Mouse, Rat

• Tissue Specificity:

  Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney.

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.

• Molecular Weight:

  39298 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Dual specificity protein phosphatase 1

• Subcellular Location:

  Nucleus.