Products for Research Use Only
RegisterLogin

BCL-2 Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC1055Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0519-EKC1055Size:1 Kit, containing one 96 Well Plate and all necessary reagents
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
The BCL-2 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor BCL-2 protein expression profile in cells. The kit can be used for measuring the relative amounts of BCL-2 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on BCL-2.
Synonyms
Apoptosis regulator Bcl-2; B-cell CLL/lymphoma 2; BCL2
Gene Name
BCL2
UniProt
P10415
Reactivity
Human, Mouse, Rat
Tissue Specificity
Expressed in a variety of tissues.
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) . May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785) .
Molecular Weight
26266 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Apoptosis regulator Bcl-2
Subcellular Location
Mitochondrion outer membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.

Related Products

CatalogName
EKC1057BCL-XL Colorimetric Cell-Based ELISA Kit
EKC1056Bcl-6 Colorimetric Cell-Based ELISA Kit
EKC2363BCL-2 (Phospho-Thr56) Colorimetric Cell-Based ELISA Kit
EKC2362BCL-2 (Phospho-Ser70) Colorimetric Cell-Based ELISA Kit
EKC2364BCL-XL (Phospho-Ser62) Colorimetric Cell-Based ELISA Kit
EKC2190BCL-XL (Phospho-Thr47) Colorimetric Cell-Based ELISA Kit
EKC1792CGK 2 Colorimetric Cell-Based ELISA
EKC1904FOXB1/2 Colorimetric Cell-Based ELISA
EKC1653TALL-2 Colorimetric Cell-Based ELISA
EKC1685EGR1/2 Colorimetric Cell-Based ELISA

Alternative Products

CatalogName
MBS9500058-01BCL-2 Colorimetric Cell-Based ELISA Kit
OKAG00548BCL-2 Colorimetric Cell-Based ELISA Kit (OKAG00548)
MBS9500060-01BCL-XL Colorimetric Cell-Based ELISA Kit
MBS9500059-01Bcl-6 Colorimetric Cell-Based ELISA Kit
MBS9518861-01Bcl-2 (Phospho-Ser70) Colorimetric Cell-Based ELISA Kit
MBS9501407-01Phospho-BCL-2 (Thr56) Colorimetric Cell-Based ELISA Kit
MBS9501406-01Phospho-BCL-2 (Ser70) Colorimetric Cell-Based ELISA Kit
OKAG00550BCL-XL Colorimetric Cell-Based ELISA Kit (OKAG00550)
OKAG00549Bcl-6 Colorimetric Cell-Based ELISA Kit (OKAG00549)
OKAG01897Phospho-BCL-2 (Thr56) Colorimetric Cell-Based ELISA Kit (OKAG01897)

Popular Products