Products for Research Use Only
RegisterLogin

MITF Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC1370Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0519-EKC1370Size:1 Kit, containing one 96 Well Plate and all necessary reagents
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
The MITF Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MITF protein expression profile in cells. The kit can be used for measuring the relative amounts of MITF in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MITF.
Synonyms
MITF M1; Microphthalmia-associated transcription factor
Gene Name
MITF
UniProt
O75030
Reactivity
Human, Mouse
Tissue Specificity
Isoform M is exclusively expressed in melanocytes and melanoma cells. Isoform A and isoform H are widely expressed in many cell types including melanocytes and retinal pigment epithelium (RPE) . Isoform C is expressed in many cell types including RPE but not in melanocyte-lineage cells. Isoform Mdel is widely expressed in melanocytes, melanoma cell lines and tissues, but almost undetectable in non-melanoma cell lines.
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to M-boxes (5'-TCATGTG-3') and symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR) . Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1) . Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
Molecular Weight
58795 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Microphthalmia-associated transcription factor
Subcellular Location
Nucleus.

Related Products

CatalogName
EKC2088MITF (Phospho-Ser180/73) Colorimetric Cell-Based ELISA Kit
EKC1359MEF2A Colorimetric Cell-Based ELISA Kit
EKC1455PHCA Colorimetric Cell-Based ELISA Kit
EKC1415Osteopontin Colorimetric Cell-Based ELISA Kit
EKC1373MKP1 Colorimetric Cell-Based ELISA Kit
EKC1112Chk1 Colorimetric Cell-Based ELISA Kit
EKC1526Smad1 Colorimetric Cell-Based ELISA Kit
EKC1555Synaptophysin Colorimetric Cell-Based ELISA Kit
EKC1598WAVE1 Colorimetric Cell-Based ELISA Kit
EKC1044ATF7 Colorimetric Cell-Based ELISA Kit

Alternative Products

CatalogName
MBS9500386-01MITF Colorimetric Cell-Based ELISA Kit
OKAG00875MITF Colorimetric Cell-Based ELISA Kit (OKAG00875)
MBS9501125-01Phospho-MITF (Ser180/73) Colorimetric Cell-Based ELISA Kit
CB5450MITF Cell-Based ELISA Kit
OKAG01615Phospho-MITF (Ser180/73) Colorimetric Cell-Based ELISA Kit (OKAG01615)
MBS9500957-01CBP Colorimetric Cell-Based ELISA Kit
MBS9500933-01PGBD1 Colorimetric Cell-Based ELISA Kit
MBS9500931-01IP3KC Colorimetric Cell-Based ELISA Kit
MBS9500927-01TF3B Colorimetric Cell-Based ELISA Kit
MBS9500925-01FOXJ1 Colorimetric Cell-Based ELISA Kit

Popular Products