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MKP1 Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC1373Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1373Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The MKP1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MKP1 protein expression profile in cells. The kit can be used for measuring the relative amounts of MKP1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MKP1.
Synonyms
3CH134; CL100; Dual specificity protein phosphatase 1; Dual specificity protein phosphatase hVH1; DUS1; DUSP1; MAP kinase phosphatase-1; MKP1; Protein-tyrosine phosphatase 3CH134; Protein-tyrosine phosphatase CL100; Protein-tyrosine phosphatase ERP; PTPN10; PTPN16; VH1
Gene Name
DUSP1 CL100 , MKP1, PTPN10 , VH1
UniProt
P28562
Reactivity
Human
Tissue Specificity
Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney.
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.
Molecular Weight
39298 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Dual specificity protein phosphatase 1
Subcellular Location
Nucleus.

UniProtKB · P28562

Dual specificity protein phosphatase 1

DUS1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P28562
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DUSP1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.1.3.16, 3.1.3.48
Processing
—
Secondary accessions
D3DQL9, Q2V508
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Cell cycleStress response

Molecular function

HydrolaseProtein phosphatase

Cellular component

Nucleus

PTM

PhosphoproteinUbl conjugation

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