ADD2 Colorimetric Cell-Based ELISA Kit

• Description:

  The ADD2 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor ADD2 protein expression profile in cells. The kit can be used for measuring the relative amounts of ADD2 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on ADD2.

• Synonyms:

  ADDB; Add97; Adducin 63; Beta adducin; Erythrocyte adducin beta subunit; adducin, beta

• Gene Name:

  ADD2

• UniProt:

  P35612

• Reactivity:

  Human, Mouse, Rat

• Tissue Specificity:

  Expressed mainly in brain, spleen, kidney cortex and medulla, and heart. Also expressed in human umbilical vein endothelial cells, human vascular smooth muscle cells, kidney tubular cells and K-562 cell line.

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to the erythrocyte membrane receptor SLC2A1/GLUT1 and may therefore provide a link between the spectrin cytoskeleton to the plasma membrane. Binds to calmodulin. Calmodulin binds preferentially to the beta subunit.

• Molecular Weight:

  80854 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Beta-adducin

• Subcellular Location:

  Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.