OCT2 Colorimetric Cell-Based ELISA Kit

• Description:

  The OCT2 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor OCT2 protein expression profile in cells. The kit can be used for measuring the relative amounts of OCT2 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on OCT2.

• Synonyms:

  POU domain class 2 transcription factor 2; Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Octamer-binding protein 2; Oct-2; Octamer-binding transcription factor 2; OTF-2; POU2F2; OCT2; OTF2

• Gene Name:

  POU2F2

• UniProt:

  P09086

• Reactivity:

  Human, Mouse

• Tissue Specificity:

  Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147.

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3') . Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter.

• Molecular Weight:

  51209 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  POU domain, class 2, transcription factor 2

• Subcellular Location:

  Cytoplasm. Nucleus.