OCT1 Colorimetric Cell-Based ELISA Kit

• Description:

  The OCT1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor OCT1 protein expression profile in cells. The kit can be used for measuring the relative amounts of OCT1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on OCT1.

• Synonyms:

  NF-A1; OCT1; OTF-1; Octamer-binding transcription factor 1; PO21; PO2F1; POU domain, class 2; transcription factor 1; POU2F1

• Gene Name:

  POU2F1

• UniProt:

  P14859

• Reactivity:

  Human, Mouse

• Tissue Specificity:

  Ubiquitous. Isoform 2 is lymphocyte-specific.

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR (By similarity) . In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.

• Molecular Weight:

  76472 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  POU domain, class 2, transcription factor 1

• Subcellular Location:

  Nucleus.