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OCT1 Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC1003Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1003Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The OCT1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor OCT1 protein expression profile in cells. The kit can be used for measuring the relative amounts of OCT1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on OCT1.
Synonyms
NF-A1; OCT1; OTF-1; Octamer-binding transcription factor 1; PO21; PO2F1; POU domain, class 2; transcription factor 1; POU2F1
Gene Name
POU2F1
UniProt
P14859
Reactivity
Human, Mouse
Tissue Specificity
Ubiquitous. Isoform 2 is lymphocyte-specific.
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR (By similarity) . In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.
Molecular Weight
76472 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
POU domain, class 2, transcription factor 1
Subcellular Location
Nucleus.

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