RET-IN-3

• UNSPSC Description:

  RET-IN-3 (compound 34) is a selective RETV804M kinase inhibitor, with an IC50 of 19 nM[1].

• Target Antigen:

  RET

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ret-in-3.html

• Smiles:

  CN(C)CCCNC1=NC2=C(C3=CC(OCO4)=C4C=C3)C=NN2C=C1

• Molecular Weight:

  339.39

• References & Citations:

  [1]Rebecca Newton, et al. Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RET V804M Kinase. ACS Med Chem Lett. 2020 Feb 28;11(4):497-505.

• Shipping Conditions:

  Room Temperature

• CAS Number:

  2414374-53-9