RET-IN-17

CAT: 0804-HY-147563Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-147563Size:1 Each
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Description
RET-IN-17 is a potent inhibitor of RET. RET-IN-17 has the potential for the research of pain associated with IBS and other gastrointestinal disorders and for the research of cancers with constitutive RET kinase activity (extracted from patent WO2016038552A1, compound 1) [1].
CAS Number
[1885880-08-9]
UNSPSC
12352005
Target
RET
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ret-in-17.html
Solubility
10 mM in DMSO
Smiles
CCOC1=CC(NC=C1C2=CC(F)=C(C=C2)CC(NC3=CC(C(NCCN(C)C)=O)=CC(C(F)(F)F)=C3)=O)=O
Molecular Formula
C27H28F4N4O4
Molecular Weight
548.53
References & Citations
[1]Michael P. Demartino, et al. Pyridone derivatives as rearranged during transfection (ret) kinase inhibitors. Patent WO2016038552A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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