RET-IN-10

• UNSPSC Description:

  RET-IN-10 is a potent inhibitor of RET. RET loss of function mutations leads to Hirschsprung's disease, while its gain of function mutations is associated with a variety of human tumors. RET-IN-10 has the potential for the research of cancer diseases (extracted from patent WO2021135938A1, compound 18)[1].

• Target Antigen:

  RET

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ret-in-10.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N#CC1=C2C(C3=CN=C(N4CCC(CC4)N=[S@](C5=CC=CC=C5)(C)=O)C=C3)=CC(C6=CN(C)N=C6)=CN2N=C1

• Molecular Weight:

  536.65

• References & Citations:

  [1]Anhu Li. Heterocyclic sulfoximine compounds and intermediates thereof, methods of preparation and applications. Patent WO2021135938A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2662622-44-6