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RET-IN-10

CAT: 0804-HY-143615Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-143615Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RET-IN-10 is a potent inhibitor of RET. RET loss of function mutations leads to Hirschsprung's disease, while its gain of function mutations is associated with a variety of human tumors. RET-IN-10 has the potential for the research of cancer diseases (extracted from patent WO2021135938A1, compound 18) [1].
CAS Number
2662622-44-6
UNSPSC
12352005
Target
RET
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ret-in-10.html
Solubility
10 mM in DMSO
Smiles
N#CC1=C2C(C3=CN=C(N4CCC(CC4)N=[S@](C5=CC=CC=C5)(C)=O)C=C3)=CC(C6=CN(C)N=C6)=CN2N=C1
Molecular Formula
C29H28N8OS
Molecular Weight
536.65
References & Citations
[1]Anhu Li. Heterocyclic sulfoximine compounds and intermediates thereof, methods of preparation and applications. Patent WO2021135938A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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