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RET-IN-26

CAT: 0804-HY-156471Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-156471Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RET-IN-26 (compound D5) is RET kinase inhibitor, with the IC50 of 0.33 μM[1].
UNSPSC
12352005
Target
RET
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ret-in-26.html
Solubility
10 mM in DMSO
Smiles
O=C1NC2=CC(C#N)=CC=C2/C1=C/C3=C(C)C(C(NCCN(CC)CC)=O)=C(C)N3
Molecular Formula
C23H27N5O2
Molecular Weight
405.49
References & Citations
[1]Zhenzhu Li, et al. Design and synthesis of indol-2-one derivatives as potential RET inhibitors. Bioorganic & Medicinal Chemistry Letters Available online 29 October 2023, 129538
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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