SC-67655

• Description:

  SC 67655 is a potent and stable pentapeptide MHC class II haplotype DR4 (DR4 Dw4 or DRB 1"0401) ligand with an IC50 of 50 nM. SC 67655 can be used for the study of autoimmune diseases[1].

• UNSPSC:

  12352209

• Target:

  TNF Receptor

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/sc-67655.html

• Smiles:

  C[C@@H](CC(N[C@@H](C(C)C)C(N1[C@H](C(N[C@@H](CC(O)=O)C(N2CCC[C@H]2C(N[C@H](C(NCCC)=O)[C@H](O)C)=O)=O)=O)CCCC1)=O)=O)C3CCCCC3

• Molecular Formula:

  C37H62N6O9

• Molecular Weight:

  734.92

• References & Citations:

  [1]S L Woulfe, et al. A peptidomimetic that specifically inhibits human leukocyte antigen DRB1*0401-restricted T cell proliferation. J Pharmacol Exp Ther. 1997 May;281 (2) :663-9.|[2]Gunnar J. Hanson, et al. (1996) . Design of MHC class II (DR4) ligands using conformationally restricted imino acids at p3 and p5. , 6 (16), 1931-1936.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [182134-00-5]