(E/Z) -PG-11047

• Description :

  (E/Z) -PG-11047 ((E/Z) -CGC-11047) is a polyamine analog with potential application in lung cancer inhibition. (E/Z) -PG-11047 effectively inhibited the growth of non-small cell and small cell lung cancer cells. (E/Z) -PG-11047 exhibits significant biochemical effects in non-small cell lung cancer cells, resulting in significant downregulation of polyamine synthetase activity. (E/Z) -PG-11047 induces polyamine metabolism, resulting in a significant reduction in polyamine levels[1].

• Product Name Alternative :

  (E/Z) -CGC-11047

• UNSPSC :

  12352211

• Target :

  Endogenous Metabolite

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/e-z-pg-11047.html

• Smiles :

  CCNCCCNC/C=C/CNCCCNCC

• Molecular Formula :

  C14H32N4

• Molecular Weight :

  256.43

• References & Citations :

  [1]In vitro and in vivo effects of the conformationally restricted polyamine analogue CGC-11047 on small cell and non-small cell lung cancer cells

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [949933-50-0]