Products for Research Use Only

ITGA2B Antibody / Integrin alpha 2b

CAT: 0800-RQ7859Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ7859Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Integrin alpha-IIb is a protein that in humans is encoded by the ITGA2B gene. It is mapped to 17q21.32. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibrinogen receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL
UniProt
P08514
Host
Rabbit
Reactivity
Human, Rat
Immunogen
E. coli-derived recombinant human protein (amino acids A675-R714) was used as the immunogen for the ITGA2B antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, FACS, Direct ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the ITGA2B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This ITGA2B antibody is available for research use only.
Storage Conditions
After reconstitution, the ITGA2B antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the ITGA2B antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE human spleen tissue with ITGA2B antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
Product Datasheet
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