Products for Research Use Only
RegisterLogin

Integrin alpha 7 Antibody / ITGA7

CAT: 0800-F54396-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-F54396-0.4MLSize:0.4 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro) . Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity) . Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:2000, Flow cytometry: 1:25 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:25, Immunofluorescence: 1:25
UniProt
Q13683
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 247-279 from the human protein was used as the immunogen for the Integrin alpha 7 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, FACS, IHC-P, IF
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Integrin alpha 7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Integrin alpha 7 antibody is available for research use only.
Storage Conditions
Aliquot the Integrin alpha 7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the Integrin alpha 7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of human 1) HeLa, 2) A431 and 3) Jurkat cell lysate with Integrin alpha 7 antibody. Predicted molecular weight ~129 kDa.

UniProtKB · Q13683

Integrin alpha-7

ITA7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13683
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ITGA7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B4E3U0, C9JMD3, C9JMZ6, O43197, Q86W93, Q9NY89, Q9UET0, Q9UEV2
Protein keywords

PTM

ADP-ribosylationCleavage on pair of basic residuesDisulfide bondGlycoprotein

Coding sequence diversity

Alternative splicing

Ligand

CalciumMetal-binding

Biological process

Cell adhesionCell shape

Disease

Congenital muscular dystrophy

Technical term

Direct protein sequencingProteomics identificationReference proteome

Molecular function

IntegrinReceptor

Cellular component

Membrane

Domain

RepeatSignalTransmembraneTransmembrane helix
Product Datasheet
Loading...

Related Products

CatalogName
F53359-0.08MLIntegrin alpha 7 Antibody
F46857-0.08MLIntegrin alpha 7 Antibody
F46857-0.4MLIntegrin alpha 7 Antibody
F53359-0.4MLIntegrin alpha 7 Antibody
FY12548ITGB7 Antibody / Integrin beta 7
R31960Integrin alpha 4 Antibody / ITGA4
RQ4096ITGA5 Antibody / Integrin alpha 5
RQ5735ITGAV Antibody / Integrin alpha V
FY12794ITGA4 Antibody / Integrin Alpha 4
RQ7713Integrin alpha 8 Antibody / ITGA8

Alternative Products

CatalogName
GTR18223947ITGA7/Integrin Alpha 7 Antibody
483754ITGA7 (Integrin, Alpha 7)
abx405915-01Integrin Alpha 7 (ITGa7) Antibody
abx346098-01Integrin alpha-7 (ITGA7) Antibody
CAU31534-01Integrin Alpha 7 (ITGa7) Polyclonal Antibody
abx346101-01Integrin alpha-7 (ITGA7) Antibody (Biotin)
abx346099-01Integrin alpha-7 (ITGA7) Antibody (HRP)
247753ITGA7 (Integrin, alpha 7, FLJ25220)
MBS2122920-01Recombinant Integrin Alpha 7 (ITGa7)
145499ITGA7 (Integrin alpha 7) (PerCP)

Popular Products