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CK1 alpha polyclonal antibody

CAT: 0384-BS62284-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS62284-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Casein kinase I (also designated CKI) and casein kinase II (CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. Casein kinase I family members, which include casein kinase Iα, Iγ, Iδ and Iε, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair, membrane trafficking, circadian rhythm, cell cycle progression, chromosome segregation, apoptosis and cellular differentiation. Casein kinase I isoform α-like (CSNK1A1L) is a 337 amino acid protein that shares a high degree of sequence similarity with the α isoform of casein kinase 1. CSNK1A1L resides in the cytoplasm and participates in the Wnt signaling pathway. By utilizing ATP within its protein kinase domain, CSNK1A1L phosphorylates a large number of proteins.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Casein kinase I isoform alpha-like; CKI-alpha-like; CK1; CSNK1A1L; Casein kinase I isoform alpha; CKI-alpha; CSNK1A1
Swiss Prot
Q8N752/P48729
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to Human CK1 alpha.
Conjugation
Unconjugated
Related Pathways
Contribution of Soluble Factors to EMT
Applications
WB IHC IF
Dilution
WB:1:500~1:1000 IHC:1:50~1:200 IF:1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 38 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CK1 alpha polyclonal antibody detects endogenous levels of CK1 alpha protein.
Applications Notes
Western blot (WB) analysis of CK1 alpha polyclonal antibody at 1:500 dilution LaneA:HEK293T whole cell lysate LaneB:A375 whole cell lysate LaneC:SGC7901 whole cell lysate LaneD:The Testis tissue lysate of Mouse LaneE:The Testis tissue lysate of Rat
Host or Source
Rabbit

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