CD97 alpha polyclonal antibody

• Background :

  This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.

• Structure Composition :

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  CD97; TM7LN1

• Swiss Prot :

  P48960

• Reactivity :

  Human, Rat

• Immunogen :

  Synthetic peptide, corresponding to Human CD97 alpha.

• Conjugation :

  Unconjugated

• Applications :

  WB IHC

• Dilution :

  WB:1:500~1:1000 IHC:1:50~1:200

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  ~ 92 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  CD97 alpha polyclonal antibody detects endogenous levels of CD97 alpha protein.

• Applications Notes :

  Western blot (WB) analysis of CD97 alpha polyclonal antibody at 1:500 dilution LaneA:Jurkat whole cell lysate LaneB:HCT116 whole cell lysate LaneC:H9C2 whole cell lysate

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4