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TNF alpha Polyclonal Antibody

CAT: 0965-JOT-AP15036-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP15036-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
CAS Number
9007-83-4
Synonyms
Tumor necrosis factor ;Cachectin;TNF-alpha;Tumor necrosis factor ligand superfamily member 2;TNF-a [Cleaved into: Tumor necrosis factor, membrane form ;N-terminal fragment;NTF; Intracellular; Tumor necrosis factor; Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a; Tumor necrosis factor, membrane form; N-terminal fragment; NTF; Intracellular domain 1; ICD1; Intracellular domain 2; ICD2; C-domain 1; C-domain 2; Tumor necrosis factor, soluble form;
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Recombinant Protein of TNF α
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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