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SRS11-92

CAT: 0804-HY-116087-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-116087-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1467047-25-1
Product Name Alternative
MK-0822
UNSPSC Description
SRS11-92, a Ferrostatin-1 (Fer-1) analogue, is a potent ferroptosis inhibitor. SRS11-92 inhibits ferroptotic cell death induced by Erastin in HT-1080 human fibrosarcoma cells (EC50=6 nM)[1].
Target Antigen
Ferroptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/srs11-92.html
Purity
99.92
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(NC2CCCCC2)C(NCC3=CC=CC=C3)=C1)OCC
Molecular Weight
352.47
References & Citations
[1]Skouta R, et al. Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models. J Am Chem Soc. 2014;136(12):4551-4556.|[2]Cotticelli MG, et al. Ferroptosis as a Novel Therapeutic Target for Friedreich's Ataxia. J Pharmacol Exp Ther. 2019;369(1):47-54.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Clinical Information
No Development Reported

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