GR 89696

• Description :

  GR 89696 is a highly selective κ2 opioid receptor agonist with potential to prevent pruritus[1].

• UNSPSC :

  12352005

• Target :

  Opioid Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/gr-89696.html

• Concentration :

  10mM

• Purity :

  99.88

• Solubility :

  DMSO : ≥ 50 mg/mL

• Smiles :

  OC(/C=C/C(O)=O)=O.ClC(C=C1CC(N2C(CN(CC2)C(OC)=O)CN3CCCC3)=O)=C(C=C1)Cl

• Molecular Formula :

  C23H29Cl2N3O7

• Molecular Weight :

  530.40

• References & Citations :

  [1]Mei-Chuan Ko, et al. Effects of atypical kappa-opioid receptor agonists on intrathecal morphine-induced itch and analgesia in primates. J Pharmacol Exp Ther. 2009 Jan;328 (1) :193-200. |[2]A Barber, et al. Effects of GR-89696 and the novel peripherally selective OP2 agonists, EMD-61569 and EMD-61747, against focal cerebral ischemia in the rat. Methods Find Exp Clin Pharmacol. 1999 Mar;21 (2) :105-13

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [126766-32-3]