GR 128107

• Description:

  GR 128107 is a competitive melatonin receptor antagonist (pKi: 9.6) [1].

• UNSPSC:

  12352005

• Target:

  Melatonin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/gr-128107.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(N1CC(CCC1)C2=CNC3=C2C=C(C=C3)OC)=O

• Molecular Formula:

  C16H20N2O2

• Molecular Weight:

  272.34

• References & Citations:

  [1]Dubocovich ML, et al. Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor. Naunyn Schmiedebergs Arch Pharmacol. 1997 Mar;355 (3) :365-75.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [190328-44-0]