Products for Research Use Only
RegisterLogin

GR 64349

CAT: 0804-HY-P1278-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P1278-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
GR 64349 is a potent and highly selective NK2 receptor peptide agonist, with an EC50 of 3.7 nM in rat colon. GR 64349 exhibits selectivity >1000 and >300-fold with respect to NK1 and NK3 receptors, respectively[1][2].
CAS Number
137593-52-3
UNSPSC
12352209
Target
Neurokinin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gr-64349.html
Purity
99.92
Solubility
H2O : ≥ 50 mg/mL
Smiles
CSCC[C@@H](C(N)=O)NC([C@@H](N1C([C@@H](CC1)NC([C@H](C(C)C)NC([C@@H](NC([C@H](CO)NC([C@H](CC(O)=O)NC([C@@H](N)CCCCN)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)CC(C)C)=O
Molecular Formula
C42H68N10O11S
Molecular Weight
921.11
References & Citations
[1]Y Chang, et al. Tachykinin receptor subtypes in the isolated guinea pig heart and their role in mediating responses to neurokinin A. J Pharmacol Exp Ther. 2000 Jul;294 (1) :147-54.|[2]M J Deal, et al. Conformationally constrained tachykinin analogues: potent and highly selective neurokinin NK-2 receptor agonists. J Med Chem. 1992 Oct 30;35 (22) :4195-204.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
NK2R

Related Products

CatalogName
HY-120840GR 100679
HY-120182GR 128107
HY-162478GR-28
HY-101248-01GR-46611
HY-19252GR-4991W93
HY-101367GR 55562
HY-107691GR 159897
HY-P991354GR-1405
HY-P11555GR-16
HY-103152-01GR 113808

Alternative Products

CatalogName
TP2023GR 64349
MBS3601556GR-64349
A23120-1GR 64349 1mg
A23120-10GR 64349 10mg
A23120-5GR 64349 5mg
MBS5817787GR 64349 TFA
TR711489Crybb3 Rat shRNA Plasmid (Locus ID 64349)
SR514459Crybb3 Rat siRNA Oligo Duplex (Locus ID 64349)
TL711489VCrybb3 Rat shRNA Lentiviral Particle (Locus ID 64349)

Popular Products