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Trimethoprim-13C3

CAT: 0804-HY-B0510S3Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0510S3Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Trimethoprim-13C3 is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc[2][3][4][5].
CAS Number
1189970-95-3
UNSPSC
12352005
Target
Antibiotic; Antifolate; Bacterial; Influenza Virus; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/trimethoprim-13c3.html
Solubility
10 mM in DMSO
Smiles
[13CH3]OC(C=C1CC2=CN=C(N)N=C2N)=C(C(O[13CH3])=C1)O[13CH3]
Molecular Formula
C11 13C3H18N4O3
Molecular Weight
293.30
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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