Prednisone-d8

• Description :

  Prednisone-d8 is the deuterium labeled Prednisone. Prednisone (Adasone) is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound.

• Product Name Alternative :

  Dehydrocortisone-d8

• UNSPSC :

  12352211

• Target :

  Apoptosis; Glucocorticoid Receptor; Isotope-Labeled Compounds

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Apoptosis; Immunology/Inflammation; Others; Vitamin D Related/Nuclear Receptor

• Field of Research :

  Inflammation/Immunology; Endocrinology; Cancer

• Purity :

  98.00

• Solubility :

  10 mM in DMSO

• Smiles :

  C[C@@]1(C2([2H])[2H])[C@](C(C([2H])([2H])O)=O)(O)CC[C@@]1([H])[C@]3([H])C[C@@]([2H])([H])C4=C([2H])C(C([2H])=C[C@]4(C)[C@@]3([2H])C2=O)=O

• Molecular Formula :

  C21H18D8O5

• Molecular Weight :

  366.48

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]RIEMER AD. Application of the newer corticosteroids to augment diuresis in congestive heart failure. Am J Cardiol. 1958 Apr;1 (4) :488-96.|[3]Zhang H, et al. Prednisone adding to usual care treatment for refractory decompensated congestive heart failure. Int Heart J. 2008 Sep;49 (5) :587-95.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported