Prednisone-d8

• Description:

  Prednisone-d8 is the deuterium labeled Prednisone. Prednisone (Adasone) is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound.

• Product Name Alternative:

  Dehydrocortisone-d8

• UNSPSC:

  12352211

• Target:

  Apoptosis; Glucocorticoid Receptor; Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Apoptosis; Immunology/Inflammation; Others; Vitamin D Related/Nuclear Receptor

• Field of Research:

  Inflammation/Immunology; Endocrinology; Cancer

• Purity:

  98.00

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@@]1 (C2 ([2H]) [2H]) [C@] (C (C ([2H]) ([2H]) O) =O) (O) CC[C@@]1 ([H]) [C@]3 ([H]) C[C@@] ([2H]) ([H]) C4=C ([2H]) C (C ([2H]) =C[C@]4 (C) [C@@]3 ([2H]) C2=O) =O

• Molecular Formula:

  C21H18D8O5

• Molecular Weight:

  366.48

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]RIEMER AD. Application of the newer corticosteroids to augment diuresis in congestive heart failure. Am J Cardiol. 1958 Apr;1 (4) :488-96.|[3]Zhang H, et al. Prednisone adding to usual care treatment for refractory decompensated congestive heart failure. Int Heart J. 2008 Sep;49 (5) :587-95.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported