Prednisone-d8

• UNSPSC Description:

  Prednisone-d8 is the deuterium labeled Prednisone. Prednisone (Adasone) is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound.

• Target Antigen:

  Apoptosis; Glucocorticoid Receptor; Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Apoptosis;Immunology/Inflammation;Others;Vitamin D Related/Nuclear Receptor

• Field of Research:

  Inflammation/Immunology; Endocrinology; Cancer

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@@]1(C2([2H])[2H])[C@](C(C([2H])([2H])O)=O)(O)CC[C@@]1([H])[C@]3([H])C[C@@]([2H])([H])C4=C([2H])C(C([2H])=C[C@]4(C)[C@@]3([2H])C2=O)=O

• Molecular Weight:

  366.48

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]RIEMER AD. Application of the newer corticosteroids to augment diuresis in congestive heart failure. Am J Cardiol. 1958 Apr;1(4):488-96.|[3]Zhang H, et al. Prednisone adding to usual care treatment for refractory decompensated congestive heart failure. Int Heart J. 2008 Sep;49(5):587-95.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported