Prednisone-d7

CAT: 0804-HY-B0214S1Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-B0214S1Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Prednisone-d7 (Dehydrocortisone-d7) is deuterium labeled Prednisone. Prednisone (Adasone) is a corticosteroid agent with anti-inflammatory and immunosuppressive effects that can be used to study diseases related to systemic lupus erythematosus[1][2].
Product Name Alternative
Dehydrocortisone-d7
UNSPSC
12352211
Target
Apoptosis; Glucocorticoid Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Immunology/Inflammation; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Inflammation/Immunology; Endocrinology; Cancer; Cardiovascular Disease
Smiles
C[C@@]1(C2([2H])[2H])[C@](C(CO)=O)(O)CC[C@@]1([H])[C@]3([H])CC([2H])([2H])C4=C([2H])C(C([2H])=C[C@]4(C)[C@@]3([2H])C2=O)=O
Molecular Formula
C21H19D7O5
Molecular Weight
365.47
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2][2]N Tomioka, et al. Effects of prednisolone on acute viral myocarditis in mice. J Am Coll Cardiol. 1986 Apr;7 (4) :868-72.|[3]RIEMER AD. Application of the newer corticosteroids to augment diuresis in congestive heart failure. Am J Cardiol. 1958 Apr;1 (4) :488-96.|[4]Qianqian Li, et al. Metabolic Profiling Reveals an Abnormal Pattern of Serum Fatty Acids in MRL/lpr Mice Under Treatment With Prednisone. Front Pharmacol. 2020 Feb 25;11:115.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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