Prednisone-d7

• Description :

  Prednisone-d7 (Dehydrocortisone-d7) is deuterium labeled Prednisone. Prednisone (Adasone) is a corticosteroid agent with anti-inflammatory and immunosuppressive effects that can be used to study diseases related to systemic lupus erythematosus[1][2].

• Product Name Alternative :

  Dehydrocortisone-d7

• UNSPSC :

  12352211

• Target :

  Apoptosis; Glucocorticoid Receptor; Isotope-Labeled Compounds

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Apoptosis; Immunology/Inflammation; Others; Vitamin D Related/Nuclear Receptor

• Field of Research :

  Inflammation/Immunology; Endocrinology; Cancer; Cardiovascular Disease

• Smiles :

  C[C@@]1(C2([2H])[2H])[C@](C(CO)=O)(O)CC[C@@]1([H])[C@]3([H])CC([2H])([2H])C4=C([2H])C(C([2H])=C[C@]4(C)[C@@]3([2H])C2=O)=O

• Molecular Formula :

  C21H19D7O5

• Molecular Weight :

  365.47

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2][2]N Tomioka, et al. Effects of prednisolone on acute viral myocarditis in mice. J Am Coll Cardiol. 1986 Apr;7 (4) :868-72.|[3]RIEMER AD. Application of the newer corticosteroids to augment diuresis in congestive heart failure. Am J Cardiol. 1958 Apr;1 (4) :488-96.|[4]Qianqian Li, et al. Metabolic Profiling Reveals an Abnormal Pattern of Serum Fatty Acids in MRL/lpr Mice Under Treatment With Prednisone. Front Pharmacol. 2020 Feb 25;11:115.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported