Prednisone

CAT: 0804-HY-B0214-01Size: 500 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B0214-01Size:500 mg
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Description
Prednisone (Adasone) is a corticosteroid agent with anti-inflammatory and immunosuppressive effects that can be used to study diseases related to systemic lupus erythematosus[1][2].
CAS Number
[53-03-2]
Product Name Alternative
Dehydrocortisone
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Glucocorticoid Receptor
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Endocrinology; Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/prednisone.html
Purity
99.86
Solubility
DMSO : 125 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
C[C@@]1(C2)[C@](C(CO)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3([H])C2=O)=O
Molecular Formula
C21H26O5
Molecular Weight
358.43
Precautions
H302, H315, H319, H335
References & Citations
[1]RIEMER AD. Application of the newer corticosteroids to augment diuresis in congestive heart failure. Am J Cardiol. 1958 Apr;1 (4) :488-96.|[2][2]N Tomioka, et al. Effects of prednisolone on acute viral myocarditis in mice. J Am Coll Cardiol. 1986 Apr;7 (4) :868-72.|[3]Qianqian Li, et al. Metabolic Profiling Reveals an Abnormal Pattern of Serum Fatty Acids in MRL/lpr Mice Under Treatment With Prednisone. Front Pharmacol. 2020 Feb 25;11:115.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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