Prednisone

• UNSPSC Description:

  Prednisone (Adasone) is a corticosteroid agent with anti-inflammatory and immunosuppressive effects that can be used to study diseases related to systemic lupus erythematosus[1][2].

• Target Antigen:

  Apoptosis; Glucocorticoid Receptor

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;Immunology/Inflammation;Vitamin D Related/Nuclear Receptor

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Endocrinology; Cancer; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/prednisone.html

• Purity:

  99.86

• Solubility:

  DMSO : 125 mg/mL (ultrasonic;warming;heat to 80°C)

• Smiles:

  C[C@@]1(C2)[C@](C(CO)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3([H])C2=O)=O

• Molecular Weight:

  358.43

• References & Citations:

  [1]RIEMER AD. Application of the newer corticosteroids to augment diuresis in congestive heart failure. Am J Cardiol. 1958 Apr;1(4):488-96.|[2][2]N Tomioka, et al. Effects of prednisolone on acute viral myocarditis in mice. J Am Coll Cardiol. 1986 Apr;7(4):868-72.|[3]Qianqian Li, et al. Metabolic Profiling Reveals an Abnormal Pattern of Serum Fatty Acids in MRL/lpr Mice Under Treatment With Prednisone. Front Pharmacol. 2020 Feb 25;11:115.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  Launched

• CAS Number:

  53-03-2