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Prednisone acetate

CAT: 0804-HY-B1832-01Size: 500 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B1832-01Size:500 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Prednisone acetate (Prednisone 21-acetate), a glucocorticoid, is an orally active Notch inhibitor. Prednisone acetate has anti-inflammatory activity and can enhance the immune response[1][2].
CAS Number
[125-10-0]
Product Name Alternative
Prednisone 21-acetate
UNSPSC
12352211
Hazard Statement
H361, H373
Target
Glucocorticoid Receptor; Interleukin Related; Notch
Type
Reference compound
Related Pathways
Immunology/Inflammation; Neuronal Signaling; Stem Cell/Wnt; Vitamin D Related/Nuclear Receptor
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer; Endocrinology; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/prednisone-acetate.html
Purity
99.92
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
C[C@@]1(C2)[C@](C(COC(C)=O)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3([H])C2=O)=O
Molecular Formula
C23H28O6
Molecular Weight
400.46
Precautions
H361, H373
References & Citations
[1]Prednisolone acetate|[2]Wang Y, et al. Intragastric administration of prednisone acetate induced impairment of hippocampal long-term potentiation [J]. Brain Research, 2023, 1805: 148270.|[3]Zhou M, Qu R, Yin X, et al. Prednisone acetate modulates Th1/Th2 and Th17/Treg cell homeostasis in experimental autoimmune uveitis via orchestrating the Notch signaling pathway [J]. International Immunopharmacology, 2023, 116: 109809.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
IL-10; IL-17; IL-4

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