Prednisone acetate

• Description :

  Prednisone acetate (Prednisone 21-acetate), a glucocorticoid, is an orally active Notch inhibitor. Prednisone acetate has anti-inflammatory activity and can enhance the immune response[1][2].

• Product Name Alternative :

  Prednisone 21-acetate

• UNSPSC :

  12352211

• Hazard Statement :

  H361, H373

• Target :

  Glucocorticoid Receptor; Interleukin Related; Notch

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation; Neuronal Signaling; Stem Cell/Wnt; Vitamin D Related/Nuclear Receptor

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cancer; Endocrinology; Inflammation/Immunology; Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/prednisone-acetate.html

• Purity :

  99.92

• Solubility :

  DMSO : 25 mg/mL (ultrasonic)

• Smiles :

  C[C@@]1(C2)[C@](C(COC(C)=O)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3([H])C2=O)=O

• Molecular Formula :

  C23H28O6

• Molecular Weight :

  400.46

• Precautions :

  H361, H373

• References & Citations :

  [1]Prednisolone acetate|[2]Wang Y, et al. Intragastric administration of prednisone acetate induced impairment of hippocampal long-term potentiation [J]. Brain Research, 2023, 1805: 148270.|[3]Zhou M, Qu R, Yin X, et al. Prednisone acetate modulates Th1/Th2 and Th17/Treg cell homeostasis in experimental autoimmune uveitis via orchestrating the Notch signaling pathway [J]. International Immunopharmacology, 2023, 116: 109809.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• Isoform :

  IL-10; IL-17; IL-4

• CAS Number :

  [125-10-0]