Prednisone acetate

• Description:

  Prednisone acetate (Prednisone 21-acetate), a glucocorticoid, is an orally active Notch inhibitor. Prednisone acetate has anti-inflammatory activity and can enhance the immune response[1][2].

• Product Name Alternative:

  Prednisone 21-acetate

• UNSPSC:

  12352211

• Hazard Statement:

  H361, H373

• Target:

  Glucocorticoid Receptor; Interleukin Related; Notch

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation; Neuronal Signaling; Stem Cell/Wnt; Vitamin D Related/Nuclear Receptor

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cancer; Endocrinology; Inflammation/Immunology; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/prednisone-acetate.html

• Purity:

  99.92

• Solubility:

  DMSO : 25 mg/mL (ultrasonic)

• Smiles:

  C[C@@]1 (C2) [C@] (C (COC (C) =O) =O) (O) CC[C@@]1 ([H]) [C@]3 ([H]) CCC4=CC (C=C[C@]4 (C) [C@@]3 ([H]) C2=O) =O

• Molecular Formula:

  C23H28O6

• Molecular Weight:

  400.46

• Precautions:

  H361, H373

• References & Citations:

  [1]Prednisolone acetate|[2]Wang Y, et al. Intragastric administration of prednisone acetate induced impairment of hippocampal long-term potentiation [J]. Brain Research, 2023, 1805: 148270.|[3]Zhou M, Qu R, Yin X, et al. Prednisone acetate modulates Th1/Th2 and Th17/Treg cell homeostasis in experimental autoimmune uveitis via orchestrating the Notch signaling pathway [J]. International Immunopharmacology, 2023, 116: 109809.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• Isoform:

  IL-10; IL-17; IL-4

• CAS Number:

  125-10-0