BWA-522 intermediate-3

CAT: 0804-HY-401056Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-401056Size:1 Each
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
BWA-522 intermediate-3 is a BWA-522 intermediate. BWA-522 is an orally available small molecule protein-targeting chimera (PROTACs) with significant degradation effect on AR-FL and AR-V7[1].
CAS Number
[3032602-27-7]
UNSPSC
12352005
Target
Drug Intermediate
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bwa-522-intermediate-3.html
Solubility
10 mM in DMSO
Smiles
CC(C)(C1=CC=C(OC[C@H](O)CCl)C=C1)C2=CC=C(OCC3CCN(C(OC(C)(C)C)=O)CC3)C=C2
Molecular Formula
C29H40ClNO5
Molecular Weight
518.08
References & Citations
[1]Zhang B, et al. Discovery of BWA-522, a First-in-Class and Orally Bioavailable PROTAC Degrader of the Androgen Receptor Targeting N-Terminal Domain for the Treatment of Prostate Cancer. J Med Chem. 2023 Aug 24;66 (16) :11158-11186.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Popular Products