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BWA-522

CAT: 0013-GTR19230909-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230909-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BWA-522 is an orally bioavailable PROTAC degrader targeting the androgen receptor's N-terminal domain, inducing apoptosis in prostate cancer cells. It effectively degrades both AR-FL and AR-V7 splice variants, demonstrating significant tumor growth inhibition in LNCaP xenograft models and reducing receptor levels in VCaP and LNCaP cell lines.
Field of Research
Cell Biology, Metabolism Research
Molecular Formula
C43H51ClN4O7
Molecular Weight
771.34
Storage Conditions
-20°C
Notes
For research use only.

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