ML-109

CAT: 0804-HY-114116-01Size: 5 mgDry Ice: NoHazardous: No

CAT#:0804-HY-114116-01Size:5 mg

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Description

ML-109 is a potent and full thyroid stimulating hormone receptor (TSHR) agonist, with an EC50 of 40 nM.

CAS Number

[1186649-91-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

TSH Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/ML-109.html

Purity

99.02

Solubility

DMSO : 83.33 mg/mL (ultrasonic)

Smiles

CC(NC1=CC=C(OCC2=CC(C(N3CC4=CC=CC=C4)NC5=C(C(O)=CC=C5)C3=O)=CC=C2OC)C=C1)=O

Molecular Formula

C31H29N3O5

Molecular Weight

523.58

Precautions

H302, H315, H319, H335

References & Citations

[1]Neumann S, et al. Small-molecule agonists for the thyrotropin receptor stimulate thyroid function in human thyrocytes and mice. Proc Natl Acad Sci U S A. 2009 Jul 28;106 (30) :12471-6.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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Alternative Products

Catalog	Name
M21973-01	ML-109
A18922-1	ML-109 1mg
A18922-5	ML-109 5mg
A18922-10	ML-109 10mg
A18922-2	ML-109 2mg
A18922-25	ML-109 25mg
A18922-50	ML-109 50mg
A18922-100	ML-109 100mg
BNUM0355-50	CD20 (109-3C2), 1mg/mL
A18922-10mM-D	ML-109 10mM * 1mL in DMSO

ML-109

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