Ensaculin (free base)

• Description :

  Ensaculin free base (KA-672) is a NMDA antagonist and have high affinities to serotonergic 5-HT1A and 5-HT7 receptors, adrenergic α1, and dopaminergic D2 and D3 receptors. Ensaculin free base is a memory-enhancing agent. Ensaculin free base has the potential as an antidementia agent acting on various transmitter systems[1].

• CAS Number :

  [155773-59-4]

• Product Name Alternative :

  KA-672; Anseculin

• UNSPSC :

  12352005

• Target :

  5-HT Receptor; Adrenergic Receptor; Dopamine Receptor; iGluR

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/ensaculin-free-base.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1OC2=C(C(C)=C1C)C=C(OCCCN3CCN(CC3)C4=C(OC)C=CC=C4)C(OC)=C2

• Molecular Formula :

  C26H32N2O5

• Molecular Weight :

  452.54

• References & Citations :

  [1]Hoerr R, Noeldner M. Ensaculin (KA-672 HCl) : a multitransmitter approach to dementia treatment. CNS Drug Rev. 2002 Summer;8 (2) :143-58.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  5-HT1 Receptor;5-HT7 Receptor