Ensaculin (free base)

Ensaculin (free base)

• CAS Number: 155773-59-4
• UNSPSC Description: Ensaculin free base (KA-672) is a NMDA antagonist and have high affinities to serotonergic 5-HT1A and 5-HT7 receptors, adrenergic α1, and dopaminergic D2 and D3 receptors. Ensaculin free base is a memory-enhancing agent. Ensaculin free base has the potential as an antidementia agent acting on various transmitter systems[1].
• Target Antigen: 5-HT Receptor; Adrenergic Receptor; Dopamine Receptor; iGluR
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Membrane Transporter/Ion Channel;Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/ensaculin-free-base.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1OC2=C(C(C)=C1C)C=C(OCCCN3CCN(CC3)C4=C(OC)C=CC=C4)C(OC)=C2
• Molecular Weight: 452.54
• References & Citations: [1]Hoerr R, Noeldner M. Ensaculin (KA-672 HCl): a multitransmitter approach to dementia treatment. CNS Drug Rev. 2002 Summer;8(2):143-58.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported