PHD-IN-3

CAT: 0804-HY-163148Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-163148Size:1 Each
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Description
PHD-IN-3 (Compound 15) is an orally active PHD inhibitor. PHD-IN-3 can be used in the study of anemia associated with chronic kidney disease[1].
CAS Number
[2924181-77-9]
UNSPSC
12352005
Target
HIF/HIF Prolyl-Hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/phd-in-3.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1CCN(C1)C2=NC3=C(C(O)=C(N=C3)C(NCC4=CN=C(C=C4)C#N)=O)C=C2
Molecular Formula
C20H18N6O3
Molecular Weight
390.40
References & Citations
[1]Xu J, et al. Discovery of Novel and Potent Prolyl Hydroxylase Domain-Containing Protein (PHD) Inhibitors for The Treatment of Anemia. J Med Chem. 2024 Jan 8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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