PHD-IN-3

• UNSPSC Description:

  PHD-IN-3 (Compound 15) is an orally active PHD inhibitor. PHD-IN-3 can be used in the study of anemia associated with chronic kidney disease[1].

• Target Antigen:

  HIF/HIF Prolyl-Hydroxylase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/phd-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@@H]1CCN(C1)C2=NC3=C(C(O)=C(N=C3)C(NCC4=CN=C(C=C4)C#N)=O)C=C2

• Molecular Weight:

  390.40

• References & Citations:

  [1]Xu J, et al. Discovery of Novel and Potent Prolyl Hydroxylase Domain-Containing Protein (PHD) Inhibitors for The Treatment of Anemia. J Med Chem. 2024 Jan 8.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2924181-77-9