PHD-IN-2

CAT: 0931-MF-0157467-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0157467-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2924182-42-1
Target
HIF/HIF Prolyl-Hydroxylase
Related Pathways
Chromatin/Epigenetic|||Metabolism
Bioactivity
PHD-IN-2 (Compound 91), a potent PHD antagonist with an IC50 of less than 5 nM, effectively stimulates erythropoietin synthesis in HEP3B cells with an EC50 of less than 2.5 ?M. It is applicable for research purposes across various medical fields, including cardiovascular, metabolic, hematological, pulmonary, kidney, liver, and wound healing disorders, as well as cancer [1].
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C(OC(C)(C)C)(=O)N1CC2(CN(C2)C3=NC4=C(C=C3)C(O)=C(C(NCC=5C=CC(C#N)=NC5)=O)N=C4)C1
Molecular Formula
C26H27N7O4
Molecular Weight
501.54
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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