PHD-IN-2

• CAS Number :

  2924182-42-1

• Target :

  HIF/HIF Prolyl-Hydroxylase

• Related Pathways :

  Chromatin/Epigenetic|||Metabolism

• Bioactivity :

  PHD-IN-2 (Compound 91), a potent PHD antagonist with an IC50 of less than 5 nM, effectively stimulates erythropoietin synthesis in HEP3B cells with an EC50 of less than 2.5 ?M. It is applicable for research purposes across various medical fields, including cardiovascular, metabolic, hematological, pulmonary, kidney, liver, and wound healing disorders, as well as cancer [1].

• Smiles :

  C(OC(C)(C)C)(=O)N1CC2(CN(C2)C3=NC4=C(C=C3)C(O)=C(C(NCC=5C=CC(C#N)=NC5)=O)N=C4)C1

• Molecular Formula :

  C26H27N7O4

• Molecular Weight :

  501.54

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C