PHD-IN-1

• CAS Number :

  2924182-31-8

• Target :

  HIF/HIF Prolyl-Hydroxylase

• Related Pathways :

  Metabolism|||Chromatin/Epigenetic

• Bioactivity :

  PHD-IN-1 (compound 80) is a potent PHD2 inhibitor with an IC50 value of ?5 nM and demonstrates EC50 values of 2.5 ?M in EPO Elisa assays in both Caco2-HIF1a-HiBiT-clone-1 and Hep3B cell lines [1].

• Smiles :

  OC=1C2=C(N=C(N3[C@@]4(CN([C@](C3)(C4)[H])C5CC5)[H])C=C2)C=NC1C(NCC=6C=CC(C#N)=NC6)=O

• Molecular Formula :

  C24H23N7O2

• Molecular Weight :

  441.49

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C