MM-02-08

• Description :

  MM-02-08 is the potent BRD4 degrader and binds to DDB1[1].

• UNSPSC :

  12352005

• Target :

  PROTACs

• Type :

  Reference compound

• Related Pathways :

  PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/mm-02-08.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(NCCCCCNC(C[C@H]1C2=NN=C(C)N2C(SC(C)=C3C)=C3C(C4=CC=C(Cl)C=C4)=N1)=O)C5=CC=C(C6CC(C7=CC(OCC8=CC=CC=C8)=CC=C7)=NN6C(CCl)=O)C=C5

• Molecular Formula :

  C49H48Cl2N8O4S

• Molecular Weight :

  915.93

• References & Citations :

  [1]Meyers M, et al. Targeted Protein Degradation through Recruitment of the CUL4A Complex Adaptor Protein DDB1. bioRxiv [Preprint]. 2023 Aug 12:2023.08.11.553046.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported