MM-02-08

CAT: 0804-HY-161167Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-161167Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MM-02-08 is the potent BRD4 degrader and binds to DDB1[1].
UNSPSC
12352005
Target
PROTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mm-02-08.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCCCCNC(C[C@H]1C2=NN=C(C)N2C(SC(C)=C3C)=C3C(C4=CC=C(Cl)C=C4)=N1)=O)C5=CC=C(C6CC(C7=CC(OCC8=CC=CC=C8)=CC=C7)=NN6C(CCl)=O)C=C5
Molecular Formula
C49H48Cl2N8O4S
Molecular Weight
915.93
References & Citations
[1]Meyers M, et al. Targeted Protein Degradation through Recruitment of the CUL4A Complex Adaptor Protein DDB1. bioRxiv [Preprint]. 2023 Aug 12:2023.08.11.553046.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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