AR-08

• Description :

  AR- 08 is an agonist of α2-adrenergic receptor, used for the treatment of attention deficit hyperactivety disorder (ADHD) .

• UNSPSC :

  12352005

• Target :

  Adrenergic Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Neurological Disease; Endocrinology

• Assay Protocol :

  https://www.medchemexpress.com/1H-Benzimidazole-7-carbonitrile,_5-[_4,5-dihydro-1H-imidazol-2-yl_amino]-4-methyl-.html

• Solubility :

  10 mM in DMSO

• Smiles :

  N#CC1=C2NC=NC2=C(C)C(NC3=NCCN3)=C1

• Molecular Formula :

  C12H12N6

• Molecular Weight :

  240.26

• References & Citations :

  [1]Clinacal information of AR-?08.|[2]Rebecca L Ashare, et al. Optimizing treatments for nicotine dependence by increasing cognitive performance during withdrawal. Expert Opin Drug Discov. Author manuscript; available in PMC 2015 Jan 8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• Isoform :

  α adrenergic receptor

• CAS Number :

  [226081-74-9]