AR-08

• UNSPSC Description:

  AR-?08 is an agonist of α2-adrenergic receptor, used for the treatment of attention deficit hyperactivety disorder (ADHD).

• Target Antigen:

  Adrenergic Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Neurological Disease; Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/1H-Benzimidazole-7-carbonitrile,_5-[_4,5-dihydro-1H-imidazol-2-yl_amino]-4-methyl-.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N#CC1=C2NC=NC2=C(C)C(NC3=NCCN3)=C1

• Molecular Weight:

  240.26

• References & Citations:

  [1]Clinacal information of AR-?08.|[2]Rebecca L Ashare, et al. Optimizing treatments for nicotine dependence by increasing cognitive performance during withdrawal. Expert Opin Drug Discov. Author manuscript; available in PMC 2015 Jan 8.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 2

• CAS Number:

  226081-74-9