CT-08

CAT: 0804-HY-P10477Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P10477Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
CT-08 (CT8, Compound 3) is a macrocyclic Sec61 modulator, blocks protein secretion in a signal sequence-dependent manner. CT-08 blocks Sec61-mediated translocation of VCAMss-GLuc into the ER, resulting in a loss of luciferase activity. CT-08 inhibits VCAM expression in transfected cells[1][2].
CAS Number
[1000770-96-6]
UNSPSC
12352209
Target
Others
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(N[C@H](C(N([C@H](C(O[C@@H](C(N[C@H](C(N([C@H](C(N[C@H](C(N1C)=O)CC(C)C)=O)CC(C)C)C)=O)C[C@H](C)CCCC)=O)CC#C)=O)C)C)=O)C[C@H](C)CCCC)[C@@H]1CC2=CC=CC=C2
Molecular Formula
C50H80N6O8
Molecular Weight
893.21
References & Citations
[1]Dustin Mcminn, et al. Preparation of thiazole carboxamides as protein secretion inhibitors for treatment of cancer and inflammation. WO2019046668A1. 2019-03-07. |[2]MacKinnon AL, et al. Photo-leucine incorporation reveals the target of a cyclodepsipeptide inhibitor of cotranslational translocation. J Am Chem Soc. 2007 Nov 28;129 (47) :14560-1.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

Related Products

CatalogName
HY-165152-01KAS 08
HY-U00371-01AR-08
HY-139144-01YM-08
HY-112902-01OGG1-IN-08
HY-136172-01ESI-08
HY-163917SalA-VS-08
HY-161167MM-02-08
HY-W04029208:0 PE
HY-108466-01Ro 08-2750
HY-170616JH-FK-08

Alternative Products

CatalogName
MF-0126786-01CT-08
MNF-08MINIPHOR 08
BA5778-1ESI-08
C07350OGG1-IN-08
BA4206-1YM-08
MBS5765865AR-08
MBS1002527Recombinant Schizosaccharomyces pombe Putative dipeptidyl aminopeptidase C2E11.08 (SPAC2E11.08, SPACUNK4.08), partial
2272/10Ro 08-2750

Popular Products