Products for Research Use Only
RegisterLogin

DHFR-IN-14

CAT: 0804-HY-161063Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-161063Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DHFR-IN-14 (compound 32) is a pyrimethamine (Pyr) -type, dihydrofolate reductase (DHFR) inhibitor with potential anticancer activity[1].
UNSPSC
12352005
Target
Dihydrofolate reductase (DHFR)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dhfr-in-14.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(CNC2=CC=C(C3=C(N)N=C(N)N=C3)C=C2[N+]([O-])=O)C=C1
Molecular Formula
C18H18N6O3
Molecular Weight
366.37
References & Citations
[1]Brown JI, et al. Investigating the anti-cancer potential of pyrimethamine analogues through a modern chemical biology lens. Eur J Med Chem. 2024 Jan 15;264:115971.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-168069DHFR-IN-20
HY-149699DHFR-IN-12
HY-159899DHFR-IN-22
HY-143236DHFR-IN-1
HY-156122DHFR-IN-8
HY-161010DHFR-IN-13
HY-179415DHFR-IN-24
HY-173220DHFR-IN-23
HY-156414DHFR-IN-11
HY-162656DHFR-IN-19

Alternative Products

CatalogName
T208976-01DHFR-IN-14
ant-596DHFR
222154-01DHFR (Dihydrofolate Reductase, DHFR) discontinued
10R-3832DHFR antibody
T208977-01DHFR-IN-15
T208229-01DHFR-IN-12
T200479-01DHFR-IN-20
388289-01DHFR discontinued
501533DHFR, NT
T61486-01DHFR-IN-4

Popular Products