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DHFR-IN-12

CAT: 0804-HY-149699Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149699Size:1 Each
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Description
DHFR-IN-12 (Compound 5c) is a DHFR inhibitor which has good antibacterial activity[1].
UNSPSC
12352005
Target
Dihydrofolate reductase (DHFR)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dhfr-in-12.html
Solubility
10 mM in DMSO
Smiles
N=C1N=C(C2=CC(OC)=C(OC)C(OC)=C2)C=C(C3=CN(C4=CC=CC=C4)N=C3C5=CC=CC=C5)N1
Molecular Formula
C28H25N5O3
Molecular Weight
479.53
References & Citations
[1]Mansour B, et al. New Pyrazole-Clubbed Pyrimidine or Pyrazoline Hybrids as Anti-Methicillin-Resistant Staphylococcus aureus Agents: Design, Synthesis, In Vitro and In Vivo Evaluation, and Molecular Modeling Simulation[J]. ACS Omega, 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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