KIO-301

• Description :

  KIO-301 is a photoswitchable HCN channel blocker, and can be used as the vitreous “light switch” molecule that reactivates retinitis pigmentosa[1].

• UNSPSC :

  12352005

• Target :

  HCN Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/kio-301.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C[N+](CC)(CC)CC)NC1=CC=C(C=C1)/N=N/C2=CC=C(N(CC)CC3=CC=CC=C3)C=C2.[Br-]

• Molecular Formula :

  C29H38BrN5O

• Molecular Weight :

  552.55

• References & Citations :

  [1]drughunter.com. Small Molecules of the Month. November 2023

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• CAS Number :

  [1643463-61-9]