KIO-301

• Description:

  KIO-301 is a photoswitchable HCN channel blocker, and can be used as the vitreous “light switch” molecule that reactivates retinitis pigmentosa[1].

• UNSPSC:

  12352005

• Target:

  HCN Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/kio-301.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C[N+](CC)(CC)CC)NC1=CC=C(C=C1)/N=N/C2=CC=C(N(CC)CC3=CC=CC=C3)C=C2.[Br-]

• Molecular Formula:

  C29H38BrN5O

• Molecular Weight:

  552.55

• References & Citations:

  [1]drughunter.com. Small Molecules of the Month. November 2023

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• CAS Number:

  [1643463-61-9]