IMB-301

CAT: 0804-HY-122156-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-122156-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
IMB-301 is a specific HIV-1 replication inhibitor that binds to hA3G (human APOBEC3G), interrupts the hA3G-Vif interaction and inhibits Vif-mediated degradation of hA3G. IMB-301 inhibits the replication of HIV-1 in H9 cells (IC50=8.63 uM) . Human APOBEC3G is a restriction factor that inhibits human immunodeficiency 1 virus (HIV-1) replication[1].
CAS Number
[64009-84-3]
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/imb-301.html
Purity
99.08
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC1=CC=C(OCCC(C2=CC=C(Cl)C=C2Cl)CN3C=CN=C3)C=C1
Molecular Formula
C19H17Cl2FN2O
Molecular Weight
379.26
References & Citations
[1]Ma L, et al. Identification of small molecule compounds targeting the interaction of HIV-1 Vif and human APOBEC3G by virtual screening and biological evaluation. Sci Rep. 2018;8 (1) :8067. Published 2018 May 23.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1

Related Products

CatalogName
HY-123277IMB-10
HY-115988-01IMB-26
HY-201628IMB-881
HY-160762IMB-H4
HY-12826-01IMB-XH1
HY-123148-01IMB-808
HY-W026339IMB-XMA0038
HY-164552-01ZNU-IMB-Z15
HY-116611IMB-YH-8
HY-175323NOTA-IMB-RGD

Alternative Products

CatalogName
BA1955-5IMB-301
MBS5814374IMB-10
MBS5775253IMB-808
T16028-01IMB-XH1
M36379-01IMB-XMA0038
MBS5805669IMB-26

Popular Products