LWG-301

CAT: 0931-MF-0146729-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0146729-01Size:25 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Target
Others|||Apoptosis|||Glutaminase
Related Pathways
Proteases/Proteasome|||Others|||Apoptosis
Bioactivity
LWG-301, an allosteric inhibitor of Glutaminase 1 (GLS1), demonstrates a potent inhibition with an IC50 value of 7 nM. It effectively impedes glutamine metabolism and elevates intracellular ROS levels, thereby inducing apoptosis. Additionally, LWG-301 shows moderate antitumor efficacy in the HCT116 xenograft model.
Smiles
CCCCC(=O)NC1=NN=C(S1)NC2CCN(CC2)C3=NN=C(C=C3)NC(=O)CC4=CC(=CC=C4)OCCCC
Molecular Formula
C28H38N8O3S
Molecular Weight
566.72
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Related Products

CatalogName
MF-0093642-01IMB-301
MF-0011888-01TAS-301
MF-0100780-01NI-301
MF-0146561-01LabMol-301
MF-0141045-01TT-301
MF-0145350-01UH 301
MF-0144175-01LEI-301
MF-0100925-01BLX-301
MF-0058962-014A7C-301
MF-0034211-01TIK-301

Alternative Products

CatalogName
MBS5815593LWG-301
MBS130610-01TAS-301
BUP07652-01IMB-301
530390NQ-301
H-3008.0001JKC-301
C06980-01RU-301
B6850-10UBP 301
B5629-25TAS 301
HY-P991412NI-301
HY-P990661SAIT-301

Popular Products