5-HT3 antagonist 5

• UNSPSC Description:

  5-HT3 antagonist 5 is a quinoxalin-2-carboxamide compound, a 5-HT3 receptor antagonist. 5-HT3 antagonist 5 exerts antagonism on 5-HT3 agonist and 2-methyl-5-HT, and shows anti-depressant effect in mice[1].

• Target Antigen:

  5-HT Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/5-ht3-antagonist-5.html

• Solubility:

  DMSO : 20.83 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C(C1=NC2=CC=CC=C2N=C1)NC3=CC=C(C=C3)OC

• Molecular Weight:

  279.29

• References & Citations:

  [1]Mahesh R, et al. Design, synthesis and structure-activity relationship of novel quinoxalin-2-carboxamides as 5-HT3 receptor antagonists for the management of depression. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6773-6.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  901599-43-7